Finally, clonidine improves neuraxial opioids and, in combination with fentanyl, interacts within an additive method, which may lessen the dose of every component by sixty% for postoperative analgesia. Clonidine treats high blood pressure level by stimulating αtwo receptors inside the brainstem, which decreases peripheral vascular resistance, decreasing blood pressure. https://mixbookmark.com/story5333339/onolidine-an-overview