Sickle cell disease (SCD) is the most common inherited hemoglobinopathy worldwide. Our previous results indicate that the reduced oxidative stress capacity of sickle erythrocytes may be caused by decreased expression of NRF2 (Nuclear factor (erythroid-derived 2)-like 2). an oxidative stress regulator. We found that activation of NRF2 with sulforaphane (SFN) in erythroid progenitors si... https://www.incredibleindiatourtravels.com/