Substitution at R3 having a halogen or alkoxy group (74f–74i) led to a slight boost in cellular potency Using the halide analogs (74g–h) showing best the potency from the group. Further more optimization brought about the discovery of 74i–j, with 74k as probably the most Lively compound while in the https://spencerumjbr.post-blogs.com/52634667/about-indazole-synthesis-review